[Significance of HLA antigen system investigation in children with malignant lymphoreticular diseases]

These last few years investigations of the HLA system antigens in children with malignant lymphoreticular diseases have been considered as highly significant. The correlation between the frequency of the HLA system antigens and malignant diseases was studied in order to assess the influence of the immunoregulating and other HLA system genes on inclination toward these diseases, their etiology and epidemiology. The study included 50 children with various forms of lymphoreticular malignant neoplasms treated at the Children's University Hospital in Belgrade.