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Preeclampsia Risks in Kidney Donors and Recipients
Pratik B Shah1, Manpreet Samra2, Michelle A Josephson3
1Section of Nephrology, University of Chicago Medicine, Chicago, IL, USA.
Current Hypertension Reports
|June 10, 2018
Summary
Women who have donated a kidney face a slightly higher risk of gestational hypertension and preeclampsia. Kidney transplant recipients also have a higher incidence of preeclampsia, necessitating specialized obstetric care.
Area of Science:
- Nephrology
- Obstetrics
- Transplantation
Background:
- Preeclampsia presents unique risks for kidney donors and recipients.
- Existing guidelines recommend counseling for kidney donors regarding pregnancy risks.
Purpose of the Study:
- To review current literature and practice guidelines on preeclampsia risks in kidney donors and recipients.
- To inform clinical practice and patient counseling.
Main Methods:
- Literature review of studies and practice guidelines.
- Analysis of recommendations from KDIGO and AST.
Main Results:
- Kidney donors have a small increased risk of gestational hypertension and preeclampsia.
- Kidney transplant recipients show a higher incidence of preeclampsia.
- Elevated pre-pregnancy creatinine is a significant risk factor.
- Preeclampsia may lead to premature delivery but does not appear to harm graft function.
Conclusions:
- Preeclampsia is a key concern for women of childbearing age who are kidney donors or recipients.
- Counseling and specialized obstetric co-management are crucial for these individuals.
- Further research into novel biomarkers for preeclampsia in this population is needed.
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