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Updated: Feb 9, 2026

Odorant-induced Responses Recorded from Olfactory Receptor Neurons using the Suction Pipette Technique
Published on: April 5, 2012
Odor-Induced Electrical and Calcium Signals from Olfactory Sensory Neurons In Situ
Xavier Grosmaitre1, Minghong Ma2
1Centre des Sciences du Goût et de l'Alimentation, UMR AgroSup, CNRS, INRA, Université de Bourgogne-Franche-Comté, Dijon, France.
Abstract:
Electrophysiological recording and optical imaging enable the characterization of membrane and odorant response properties of olfactory sensory neurons (OSNs) in the nasal neuroepithelium. Here we describe a method to record the responses of mammalian OSNs to odorant stimulations in an ex vivo preparation of intact olfactory epithelium. The responses of individual OSNs with defined odorant receptor types can be monitored via patch-clamp recording or calcium imaging.
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