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Biophysical and biochemical roles of Moringa oleifera leaves as radioprotector
Azhar M Elwan1, Aida A Salama2, Abdelbaset M Sayed1
1Biochemistry Dept, National Research Centre (NRC), 33 El Bohouth St., Dokki, 12622, Giza, Egypt.
Abstract:
It has been found that medicinal plants have chemical and/or therapeutic effects on different diseases related to oxidative damage. This work investigates the use of ethanolic Moringa oleifera leaves extract; as a protective and/or therapeutic agent against damage induced by high acute dose of ionizing radiation. Also, this study aims to explore the associations of electrical properties (relaxation time and DC conductivity of bone marrow) with biochemical markers (SOD, CAT and GSH) to detect and prognosticate radiation effects. Biophysical and biochemical data revealed that Moringa extract can improve the electrical properties of bone marrow and the antioxidants levels in the blood. They also showed that the feeding of Moringa leaves extract post irradiation is preferred to recover rapidly and continuously from radiation effects.
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