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Isolation and Quantification of Epstein-Barr Virus from the P3HR1 Cell Line
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Epstein-Barr virus (EBV)-associated lymphoid proliferations, a 2018 update
Sherif A Rezk1, Xiaohui Zhao1, Lawrence M Weiss2
1Department of Pathology & Laboratory Medicine, University of California Irvine (UCI) Medical Center, Orange, 92868, CA.
Human Pathology
|June 10, 2018
Summary
Epstein-Barr virus (EBV) is linked to various cancers. This review details recent advancements in understanding EBV-associated lymphoid and histiocytic proliferations, covering diverse categories.
Area of Science:
- Oncology
- Virology
- Immunology
Background:
- Epstein-Barr virus (EBV) is associated with numerous human neoplasms.
- Significant advancements in understanding EBV-associated lymphoproliferative disorders have occurred since 2007.
Purpose of the Study:
- To review recent progress in EBV-associated lymphoid/histiocytic proliferations.
- To categorize these proliferations into distinct groups for clarity.
Main Methods:
- Literature review of recent studies on EBV-associated lymphoid/histiocytic proliferations.
- Classification of proliferations based on cell type and clinical context.
Main Results:
- Recent research has expanded knowledge on EBV's role in various lymphoid/histiocytic conditions.
- Key advances are noted across reactive, B cell, T/NK cell, immunodeficiency-related, and histiocytic/dendritic cell proliferations.
Conclusions:
- A comprehensive understanding of EBV-associated proliferations is crucial for diagnosis and treatment.
- Continued research is vital to further elucidate the pathogenesis and management of these conditions.
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