Related Experiment Video
Updated: Feb 9, 2026

08:50
Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
16.8K
[Immunizations for patients with kidney disease].
Claire Trivin-Avillach1, Éric Thervet2
1Renal department, Boston University Medical Center, Boston, MA, États-Unis.
Summary
People with chronic kidney disease (CKD) face higher infection risks. This review synthesizes guidelines for adapting immunization practices in nephrology to improve patient outcomes.
Area of Science:
- Nephrology
- Immunology
- Public Health
Background:
- Chronic kidney disease (CKD) significantly increases susceptibility to infectious complications.
- Infections in CKD patients can stem from nephropathy, immunosuppressive treatments, or dialysis.
- Vaccination responses may be less effective in CKD patients, necessitating tailored strategies.
Purpose of the Study:
- To review and synthesize current guidelines for immunization in nephrology.
- To address the unique challenges of vaccination in patients with chronic kidney disease.
- To provide a practical resource for adapting immunization practices in nephrology.
Main Methods:
- Systematic review of existing international and national guidelines on immunization in CKD.
- Analysis of evidence regarding vaccine efficacy and safety in nephrology patients.
- Synthesis of recommendations for specific vaccines and patient populations within nephrology.
Main Results:
- Immunization provides benefits in CKD patients, similar to the general population, despite potentially reduced vaccine response.
- Specific adaptations in immunization schedules and vaccine types are often required for individuals with CKD.
- Guidelines address various aspects, including timing, vaccine selection, and post-vaccination monitoring in nephrology.
Conclusions:
- Adapting immunization practices is crucial for mitigating infection risks in chronic kidney disease patients.
- Adherence to updated guidelines ensures optimal vaccine benefits and safety in nephrology.
- Further research may refine immunization strategies for diverse CKD populations.
Related Concept Videos
Chronic Kidney Disease I: Introduction
742
Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
742
Chronic Kidney Disease II: Clinical Manifestations
674
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
674
Chronic Kidney Disease III: Interprofessional Care
482
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
482
Chronic Kidney Disease IV: Nursing Management
404
Nursing management is essential for preventing complications, maintaining stability, and improving patients' quality of life in chronic kidney disease (CKD). By using a structured approach, nurses help slow CKD progression and support effective patient care.1. Comprehensive patient assessmentEffective management begins with nurses reviewing the patient’s medical history, and identifying key risk factors like diabetes, hypertension, and nephrotoxic drug use. Nurses assess signs of...
404
What is the Immune System?
130.8K
Overview
130.8K
Kidney Structure
75.4K
The kidneys are two large bean-shaped organs located in the upper abdomen. They filter the blood several times a day to remove toxins and rebalance water and electrolytes of the circulatory system via the renal veins. The kidneys receive blood directly from the heart via the renal arteries. These arteries enter the kidney at the hilum, the concave surface of the bean, where they branch and divide into smaller vessels and capillaries.
75.4K

