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Expression and Purification of Virus-like Particles for Vaccination
Published on: June 2, 2016
Pertussis vaccination in a cohort of older Australian adults following a cocooning vaccination program
A Dyda1, P McIntyre2, S Karki1
1School of Public Health and Community Medicine, UNSW, Sydney, NSW, Australia.
Background:
While recommendations to vaccinate adults against pertussis exist, information on uptake for adult tetanus-diphtheria-pertussis vaccine (Tdap) among older adults is limited.
Methods:
We used data from the 45 and Up Study, a prospective cohort of adults aged ≥45 years who completed a questionnaire between 2012 and 2014 asking about pertussis vaccination. We evaluated Tdap uptake following a program providing free vaccine for adults in contact with young children between 2009 and 2012.
Results:
Among 91,432 adults (mean age = 66.3 years, SD = 9.6), 3.1% (n = 2823) reported receiving Tdap prior to the program. This increased seven-fold to 21.8% (n = 19898) after the program finished. Tdap coverage was almost twice as high in women compared to men and among adults more likely to be grandparents than those not.
Conclusion:
These findings suggest that funding for a targeted program can help to substantially increase vaccination coverage as well as decrease disparities in the uptake of Tdap in different sub-groups.
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