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Optical Sectioning and Visualization of the Intervertebral Disc from Embryonic Development to Degeneration

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Optic Disc Pit Maculopathy: A Two-Year Nationwide Prospective Population-based Study.

David H W Steel¹, Javid Suleman², Declan C Murphy³

¹Sunderland Eye Infirmary, Sunderland, United Kingdom; Institute of Genetic Medicine, Newcastle University, Newcastle Upon Tyne, United Kingdom.

|June 12, 2018

Summary

This summary is machine-generated.

Optic disc pit maculopathy (ODPM) affects approximately 1 in 2 million people annually in the UK. Subretinal fluid presence indicates worse vision and higher deterioration risk, while surgery offers a 75% anatomical success rate.

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Area of Science:

Ophthalmology
Retinal Diseases
Ophthalmic Epidemiology

Background:

Optic disc pit maculopathy (ODPM) is a rare condition affecting vision.
Understanding its incidence and clinical course is crucial for patient management.

Purpose of the Study:

To determine the incidence, clinical features, treatment, and outcomes of ODPM in the United Kingdom.
To analyze the impact of fluid accumulation on visual acuity and disease progression.

Main Methods:

A 2-year nationwide prospective population-based study.
Data collected via questionnaires from UK ophthalmologists reporting new ODPM cases.
Follow-up at 12 months included visual acuity, OCT findings, and management details.

Main Results:

Annual incidence of ODPM is approximately 1 per 2 million in the UK, with 74 new cases identified.
Subretinal fluid (SRF) was present in 61% of patients, associated with worse vision and foveal involvement.
Surgery achieved anatomical success in 76% of cases, with 60% experiencing significant visual acuity improvement.

Conclusions:

The study defines ODPM incidence and key presenting features in the UK.
Subretinal fluid is a negative prognostic indicator, while intraretinal fluid may be more stable.
Surgical intervention is effective for achieving anatomical success in ODPM.