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Updated: Feb 9, 2026

Cell Population Analyses During Skin Carcinogenesis
Published on: August 21, 2013
Lipid metabolism and carcinogenesis, cancer development
Jia Long1, Chan-Juan Zhang1, Neng Zhu2
1School of Pharmacy, Hunan University of Chinese Medicine Changsha, Hunan, China.
Abstract:
The disorder of lipid metabolism is pathologically linked to hyperlipidemia, lipid storage disease, obesity and other related diseases. Intriguingly, recent studies have revealed that lipid metabolism disorders play an important role in carcinogenesis and development as well, since they cause abnormal expression of various genes, proteins, and dysregulation of cytokines and signaling pathways. More importantly, lipid-lowering drugs and anti-lipid per-oxidation treatment have been showing their advantages in clinic, in comparison with other anti-cancer drugs with high toxicity. Thus, further elucidation of molecular mechanism between lipid metabolism and cancer is essential in developing novel diagnostic biomarkers and therapeutic targets of human cancers.
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