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Microfluidics Based Magnetophoresis: A Review.

Fadi Alnaimat1, Sawsan Dagher1, Bobby Mathew1

  • 1Mechanical Engineering Department, College of Engineering, UAE University, Al Ain, Abu Dhabi, UAE.

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Summary

Magnetophoresis uses magnetic forces for micro-scale manipulation in microfluidic devices. This cost-effective, biocompatible technique efficiently traps, separates, and switches cells and microparticles.

Keywords:
Applicationsmagnetophoresismicrofluidicsnanoparticlesnanotechnology

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Area of Science:

  • Biophysics
  • Microfluidics
  • Biotechnology

Background:

  • Magnetophoresis is the manipulation of micro-scale entities using magnetic forces.
  • It has gained interest for its simplicity, cost-effectiveness, efficiency, and biocompatibility in microfluidic applications.

Purpose of the Study:

  • To review the theory and applications of magnetophoresis in microfluidic devices.
  • To discuss magnetic field gradient sources and the state-of-the-art in magnetophoresis-based microfluidic systems.

Main Methods:

  • Review of magnetophoresis principles and magnetic field gradient generation.
  • Analysis of microfluidic devices utilizing positive- and negative-magnetophoresis for particle manipulation.

Main Results:

  • Magnetophoresis enables efficient manipulation of micro-scale entities like cells and microparticles.
  • Applications include trapping, focusing, separation, and switching within microfluidic systems.

Conclusions:

  • Magnetophoresis is a versatile and promising technology for microfluidic applications.
  • The field shows potential for further advancements in micro-scale entity manipulation.