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THE ROLE OF CALCIUM-REGULATING SYSTEM IN THE PATHOGENESIS AND SANOGENESIS OF PEPTIC ULCER DISEASE AND POSSIBILITY OF
Aim:
to determine the condition calcium-regulating system, calcium-phosphate balance in the period of recurrence of peptic ulcer disease and possibility of correction changes in calcium-regulating system (drugs calcitonin, calcium channel-blocking agent, biphosphonate).
Materials And Methods:
220 patients with peptic ulcer recurrence were examined with examinations of parathyrin, calcitonin, calcium and phosphorus in blood, secretbry and motor functions of a stomach.
Results:
it was established that a recurrence of peptic ulcer disease accompanied by significant increase of parathyrin and calcium in blood, small increase of calcitonin in blood, significant decrease phosphorus in blood. These changes, accompanied by a significant increase of secretory and motor functions of a stomach, reducing production gastromucoproteids. Application in the treatment of peptic ulcer disease calcitrinum, nifedipinum and etidronic acid leads to a significant clinical effect, the normalization of the level of calcium in blood and functions of the stomach.
Conclusion:
recurrence of peptic ulcer disease has changes in calcium-regulating system. Application in complex treatment of recurrence of peptic hormone C-cells of the thyroid - calcitrinum, calcium channel-blocking agent -- nifedipine and biphosphonate - etidronic acid are clinically effective.
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