THE PSYCHO-PHYSIOLOGICAL STATUS IN CELIAC DISEASE.

Area of Science:

• Gastroenterology and Psychology

Background:

• Celiac disease is an autoimmune disorder triggered by gluten ingestion.
• It affects multiple physiological systems and impacts patient quality of life.

Purpose of the Study:

• To investigate the physiological status and psychophysiological manifestations in individuals with celiac disease.
• To understand the relationship between disease severity, quality of life, and psychological symptoms.

Main Methods:

• A comprehensive study involving 35 participants (20 women, 15 men) aged 19-52 years with celiac disease.
• Diagnosis confirmed through clinical, anamnestic, endoscopic, histomorphological, immunological, and genetic evaluations.
• Psychophysiological analysis was conducted to assess mental and emotional states.

Main Results:

• Celiac disease is associated with significant alterations in physiological status and reduced quality of life.
• Psychophysiological analysis revealed prevalent reactions including anxiety, anxiety-phobic, neurotic, affective, and hypochondriacal symptoms.
• The study highlighted the body's adaptive physiological capacity in developing tolerance to psycho-vegetative and depressive disorders.

Conclusions:

• Celiac disease presents with a distinct psychophysiological profile, including significant anxiety and depressive symptoms.
• Adaptive physiological mechanisms play a crucial role in managing the psycho-vegetative and mood disturbances associated with celiac disease.