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Updated: Feb 9, 2026

Paradigms of Lower Extremity Electrical Stimulation Training After Spinal Cord Injury
Published on: February 1, 2018
[Nusinersen in the treatment of spinal muscular atrophy]
Gabriella Sinkó1, Zsuzsanna Kiss2, Bernadette Kalman3,4
1Markusovszky Egyetemi Oktatókórház, Csecsemô- és Gyermekgyógyászati Osztály, Szombathely.
Abstract:
Until recently, the diagnosis of spinal muscular atrophy (SMA) has been associated with severe life-long motor disability in adults and with early death in infants. The new experimental therapeutic approaches of the last few years have become more and more promising, while nusinersen was approved for the treatment of SMA in December 2016 in the USA, and in May 2017 in Hungary. Our paper presents mechanisms and clinical benefits of this new medication, and highlights some of the other therapeutic strategies still in experimental stages.
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