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[Use of silver coating in tumoral prosthetic surgery: influence on infection rate.]

Andrés Aguilar Ezquerra1, Antonio Peguero Bona

  • 1Hospital universitario Miguel Servet. aaguilarez@gmail.com.

Revista De La Facultad De Ciencias Medicas (Cordoba, Argentina)
|June 12, 2018
PubMed
Abstract

Insights

Silver coating on megaprostheses significantly reduces infection rates in oncological surgery patients. This study found a 10% infection rate in silver-coated implants, lower than non-coated alternatives.

Area of Science:

  • Orthopedic Surgery
  • Oncology
  • Biomaterials Science

Background:

  • Megaprostheses are crucial in oncological surgery but are prone to high infection rates.
  • Periprosthetic infections pose a significant challenge, impacting patient outcomes and treatment success.

Purpose of the Study:

  • To evaluate the efficacy of silver-coated megaprostheses in reducing infection rates.
  • To assess the long-term outcomes of patients receiving silver-coated Mutars® arthroplasty.

Main Methods:

  • A cohort of 30 patients received silver-coated Mutars® arthroplasty for neoplastic disease or periprosthetic fractures.
  • Patients underwent clinical and analytical monitoring with a minimum 4-year follow-up period.

Main Results:

  • Three infections (10% of patients) were detected during the follow-up period.
  • The observed infection rate is lower compared to studies using non-silver-coated prostheses.

Conclusions:

  • Silver coating on megaprostheses appears to be an effective strategy for decreasing the incidence of periprosthetic infections.
  • This finding suggests a potential improvement in the safety and efficacy of oncological surgical reconstructions.
Keywords:
silver coatingmegaprosthesesinfection

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