Related Experiment Video
Updated: Feb 9, 2026
07:12
Using Informational Connectivity to Measure the Synchronous Emergence of fMRI Multi-voxel Information Across Time
Published on: July 1, 2014
12.7K
On the relationship between instantaneous phase synchrony and correlation-based sliding windows for time-resolved
Mangor Pedersen1, Amir Omidvarnia1, Andrew Zalesky2
1The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Melbourne, VIC, Australia.
Neuroimage
|June 12, 2018
Summary
Instantaneous phase synchrony analysis (IPSA) and correlation-based sliding window analysis (CSWA) offer comparable time-resolved functional MRI connectivity insights. IPSA is effective with narrow-band filtering and avoids arbitrary window selection, unlike CSWA.
Area of Science:
- Neuroimaging
- Computational Neuroscience
- Data Analysis
Background:
- Time-resolved functional MRI (fMRI) connectivity analysis is crucial for understanding dynamic brain function.
- Correlation-based sliding window analysis (CSWA) is a common but potentially limited method for this analysis.
- Instantaneous phase synchrony analysis (IPSA) offers single time-point resolution, gaining popularity for time-resolved fMRI connectivity.
Purpose of the Study:
- To systematically compare CSWA and IPSA on temporal, topological, and anatomical levels.
- To evaluate the influence of window length and filtering on the association between CSWA and IPSA.
- To determine the comparability of these methods for characterizing time-resolved fMRI connectivity.
Main Methods:
- Utilized resting-state fMRI data from two cohorts with differing temporal resolutions (TR=0.72s and 3s).
- Calculated tapered CSWA across various window lengths and compared results with IPSA.
- Analyzed connectivity dynamics, topological properties, and anatomical similarities across methods.
Main Results:
- A strong association was found between IPSA and CSWA absolute values, particularly with shorter CSWA window lengths (~20s).
- Narrow-band fMRI filtering (0.03-0.07 Hz) enhanced the relationship between IPSA and CSWA.
- IPSA and CSWA showed anatomical similarities in key brain networks like the default mode network and sensory cortex.
Conclusions:
- IPSA and CSWA provide comparable characterizations of time-resolved fMRI connectivity when window lengths are appropriately chosen.
- IPSA offers advantages by avoiding semi-arbitrary window length and overlap selections, though it requires narrow-band filtering.
- The study provides insights into selecting appropriate methods and parameters for time-resolved fMRI connectivity analysis.
Related Concept Videos
02:20Correlations
36.4K
Correlation means that there is a relationship between two or more variables (such as ice cream consumption and crime), but this relationship does not necessarily imply cause and effect. When two variables are correlated, it simply means that as one variable changes, so does the other. We can measure correlation by calculating a statistic known as a correlation coefficient. A correlation coefficient is a number from -1 to +1 that indicates the strength and direction of the relationship between...
36.4K
01:27Correlation and Causation
42.9K
Statistical tests can calculate whether there is a relationship, or correlation, between independent and dependent variables. An indirect relationship of the variables signifies a correlation, while a direct relationship shows causation. If it is determined that no connection exists between the variables, then the correlation is a coincidence.
Correlation versus Causation
If the dependent variable increases or decreases when the independent variable increases, there is a positive or negative...
Correlation versus Causation
If the dependent variable increases or decreases when the independent variable increases, there is a positive or negative...
42.9K
01:15Drug Concentration Versus Time Correlation
2.2K
The plasma drug concentration-time curve is a crucial tool in pharmacokinetics, representing the drug's concentration in plasma at different time intervals post-administration. This curve illustrates the drug's journey from absorption into the systemic circulation, distribution to body tissues, and eventual elimination through excretion or biotransformation.
Two pivotal parameters are the minimum effective concentration (MEC) and the minimum toxic concentration (MTC). The MEC is the...
Two pivotal parameters are the minimum effective concentration (MEC) and the minimum toxic concentration (MTC). The MEC is the...
2.2K
02:12Relationship Formation
46.2K
What do you think is the single most influential factor in determining with whom you become friends and whom you form romantic relationships? You might be surprised to learn that the answer is simple: the people with whom you have the most contact. This most important factor is proximity. You are more likely to be friends with people you have regular contact with. For example, there are decades of research that shows that you are more likely to become friends with people who live in your dorm,...
46.2K
01:10Instantaneous Velocity - II
13.2K
Instantaneous velocity is the quantity that measures how fast an object is moving along its path. In other words, the instantaneous velocity of an object is the limit of the average velocity as the elapsed time approaches zero, or the derivative of displacement with respect to time. Like average velocity, the instantaneous velocity is a vector with the dimensions of length per unit time. Instantaneous velocity can have both positive and negative values. The instantaneous velocity can be...
13.2K
01:16Instantaneous Acceleration
23.2K
Acceleration is in the direction of the change in velocity, but it is not always in the direction of motion. When an object slows down, its acceleration is opposite to the direction of its motion. Although commonly referred to as deceleration, this causes confusion in our analysis as deceleration is not a vector, and does not point to a specific direction with respect to a coordinate system. Therefore, the term deceleration is not used. For example, when a subway train slows down, it...
23.2K