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Studies on the Biocompatibility of Poly(diethyl vinyl-phosphonate) with a New Fluorescent Marker
Christina Schwarzenböck1, Sergei I Vagin1, Werner R Heinz1
1Wacker Chair of Macromolecular Chemistry, Technical University of Munich, Lichtenbergstr. 4, 85748, Garching, Germany.
Abstract:
Utilization of group transfer polymerization for the synthesis of poly(diethyl vinylphosphonate) (PDEVP) allows its controlled end-group functionalization. Thus, a new fluorescent chromophore/PDEVP conjugate is prepared and subjected to biocompatibility tests on two different human cell lines. In contrast to the previous studies, the tagged polymer is not absorbed by cells from the solution and has nearly no impact on cell mortality rate.
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