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Updated: Feb 9, 2026

Primary Culture of Human Vestibular Schwannomas
Published on: July 20, 2014
Glottic neurogenic tumor: A highly uncommon site for schwannomas
Shuchita Singh1, Rakesh Kumar1, Maitrayee Roy2
1Department of Otorhinolaryngology, All India Institute of Medical Sciences, New Delhi, India.
Abstract:
Schwannomas are benign encapsulated neurogenic tumors, arising from Schwann cells embedded in neurilemal sheath as multinucleated syncytial network. Head and neck schwannomas account for 25%-45% of all schwannomas, majority developing in parapharyngeal space. Laryngeal schwannoma in itself is a rarity, and a glottic origin further complicates its diagnosis. To the best of our knowledge, this is the second case of glottic schwannoma being reported in medical literature. Symptomatology is attributable to mass effect of a slow-growing laryngeal tumor, ranging from sore throat to stridor. The gold standard method for their excision is still debatable. For small tumors, endoscopic or direct laryngoscopic approach is preferred, but for large glottic tumors, external approach is advocated for better exposure and facilitating mucosal grafting. Index case is being presented not only for its rare site of origin, but also to stress on the importance of meticulous histopathological examination to advocate appropriate treatment.
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