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Updated: Feb 9, 2026

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Sellar Paraganglioma.

Manjiri Karlekar1, Sanjeet Kumar, Swati Jadhav

  • 1From the Department of Endocrinology, Seth GS Medical College, Parel, Mumbai, India.

Clinical Nuclear Medicine
|June 13, 2018
PubMed
Summary

Sellar paragangliomas are rare neuroendocrine tumors. This case highlights a large sellar paraganglioma with extensive spread, treated with surgery and radiotherapy, confirmed by DOTANOC PET-CT.

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Area of Science:

  • Neuroendocrinology
  • Neurosurgery
  • Oncology

Background:

  • Sellar and suprasellar paragangliomas are exceptionally rare tumors.
  • Paragangliomas arise from neuroendocrine cells, typically in the head and neck, but rarely in the sellar region.

Observation:

  • A 19-year-old male presented with a sellar paraganglioma.
  • The tumor exhibited significant extension into the parasellar and posterior pontine regions.
  • The patient underwent multiple transcranial surgical interventions and radiotherapy.

Findings:

  • The sellar paraganglioma demonstrated avid uptake on a Gallium-68 DOTANOC Positron Emission Tomography-Computed Tomography (Ga DOTANOC PET-CT) scan.
  • This finding confirmed the neuroendocrine nature of the tumor.

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Implications:

  • This case underscores the importance of considering rare neuroendocrine tumors in the sellar region.
  • Advanced imaging like Ga DOTANOC PET-CT is crucial for diagnosis and characterizing neuroendocrine tumors.
  • Multimodal treatment including surgery and radiotherapy may be necessary for extensive sellar paragangliomas.