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Prostate-Specific Membrane Antigen Expression in Distal Radius Fracture
Sebastian Hoberück1, Enrico Michler1, Daniel Kaiser2
1From the Departments of Nuclear Medicine.
Abstract:
A 79-year old man with prostate cancer under active surveillance for 5 years was referred for a PSMA-PET/MRI for re-evaluation because of a rising prostate-specific antigen value. PET/MRI revealed a ribbonlike tracer accumulation in a healing fracture of the distal radius. This case illustrates that PSMA expression may occur in healing bone fractures in the distal radius. It can be assumed that benign causes of tracer accumulations in the upper extremities are missed in PET/CT due to elevated position of the arms during image acquisition.
Insights
Prostate-specific membrane antigen (PSMA) PET/MRI revealed unexpected tracer accumulation in a healing distal radius fracture. This highlights potential benign causes of PSMA uptake in bone, often missed in standard imaging.
Area of Science:
- Nuclear Medicine
- Radiology
- Oncology
Background:
- Prostate-specific membrane antigen (PSMA) PET imaging is crucial for prostate cancer staging and recurrence detection.
- Rising prostate-specific antigen (PSA) levels in patients with prostate cancer necessitate re-evaluation.
- Standard imaging protocols may overlook benign causes of tracer accumulation, especially in extremities.
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