A rare fungus on the rise: Candida auris

Yuman Lee1, Hongkai Bao2, Sagar Viramgama2

  • 1Department of Clinical Health Professions, St. John's University College of Pharmacy and Health Sciences, Queens, NY. leey2@stjohns.edu.

Abstract

Insights

Candida auris is a growing fungal threat causing invasive infections. This emerging pathogen is difficult to identify and resistant to antifungals, requiring specific treatment and infection control strategies.

Area of Science:

  • Medical Mycology
  • Infectious Diseases
  • Public Health

Background:

  • Candida auris is an emerging fungal pathogen first identified in 2009.
  • Cases of Candida auris infection have increased globally, with significant outbreaks reported in the United States since 2017.
  • Identified risk factors include hospitalization, catheterization, and recent surgery.

Purpose of the Study:

  • To provide an overview of the increasing health threat posed by Candida auris.
  • To review current literature and CDC recommendations for Candida auris identification, treatment, and infection control.

Main Methods:

  • Literature review
  • Analysis of Centers for Disease Control and Prevention (CDC) data and recommendations.

Main Results:

  • Candida auris presents major diagnostic challenges due to misidentification by conventional laboratory methods.
  • The fungus exhibits resistance to commonly used antifungal agents, complicating treatment.
  • Effective infection control and prevention measures are crucial but challenging to implement due to identification and resistance issues.

Conclusions:

  • Candida auris is an emerging fungus with the potential to cause severe invasive infections.
  • Echinocandins are the recommended first-line treatment for Candida auris infections in patients aged 2 months and older.
  • Antimicrobial stewardship is vital for managing and preventing Candida auris infections.

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