Related Experiment Video
Updated: Feb 9, 2026

The Innovation Arena: A Method for Comparing Innovative Problem-Solving Across Groups
Published on: May 13, 2022
[Concise analysis for innovation of pioneering and follow-on drugs]
Abstract:
More attention has been paid to the pioneering drug innovation since the new millennium, while the creation space of fast-followed drugs is shrinking due to the serious risks observed in the clinical phases following marketing. Innovative drug discovery aiming at the brand new target is dependent on the breakthrough in basic biology, followed by chemical biology, and medicinal chemistry. This roadmap requires harmonious environment and free exploration atmosphere, while mandatory planning unlikely accelerates drug discovery. This article concisely analyzes several critical aspects of current status of drug discovery.
Related Concept Videos
Therapeutic Drug Monitoring: Drug Analysis Methods
Pharmacokinetics: Drug–Drug Interactions
Bioequivalence of Drugs: Drugs with Multiple Indications
FDA Approved Drugs: Changes to Approved Drugs
Factors Influencing Drug Absorption: Drug Dissolution
Factors Affecting Protein-Drug Binding: Drug-Related Factors
One crucial factor in drug-protein binding is the drug's lipophilicity or its affinity for fat. More lipophilic drugs tend to have higher binding extents. For example, highly lipophilic drugs like cloxacillin exhibit substantial protein binding, with as much as 95% of the drug binding to proteins. In...

