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Updated: Feb 9, 2026

Measuring Local Anaphylaxis in Mice
Published on: October 14, 2014
Anaphylaxis triggered by prick test with latex extract: a case report
Leonardo Oliveira Mendonça1, Cynthia Mafra Fonseca de Lima2, Priscilla Rios Cordeiro Macedo3
1MD. Postgraduate Fellow, Clinical Immunology and Allergy Division, Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo (SP), Brazil.
Context:
Adverse reactions associated with prick tests are rare but may be present as serious systemic reactions.
Case Report:
A 38-year-old female nursing technician complained of three episodes of anaphylaxis in one year, all in the workplace. To investigate latex allergy, the patient underwent the prick test with latex, and immediately developed a rash, itchy skin, hoarseness, dyspnea and dry cough. Her condition improved promptly after appropriate measures were established for controlling her anaphylaxis.
Conclusion:
The skin test must be performed under medical supervision, since complications that can lead to life-threatening reactions, if support measures are not readily implemented, have been attributed to this test.
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