Related Experiment Video
Updated: Feb 9, 2026

Measuring Local Anaphylaxis in Mice
Published on: October 14, 2014
Anaphylaxis triggered by prick test with latex extract: a case report.
Leonardo Oliveira Mendonça1, Cynthia Mafra Fonseca de Lima2, Priscilla Rios Cordeiro Macedo3
1MD. Postgraduate Fellow, Clinical Immunology and Allergy Division, Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo (SP), Brazil.
Prick tests for allergies, like latex, can cause serious systemic reactions. Medical supervision is crucial during skin testing to manage potential anaphylaxis and ensure prompt treatment.
Area of Science:
- Allergy and Immunology
- Occupational Health
Background:
- Adverse reactions to skin prick tests are uncommon but can manifest as severe systemic events.
- Occupational exposure to allergens, such as latex, can trigger allergic responses in healthcare workers.
Observation:
- A 38-year-old female nursing technician experienced three episodes of anaphylaxis within a year, all linked to her workplace.
- Following a latex prick test, the patient rapidly developed symptoms including rash, pruritus, hoarseness, dyspnea, and dry cough.
- The patient's anaphylactic symptoms resolved promptly with immediate medical intervention and supportive care.
Findings:
- Skin prick testing, particularly with allergens like latex, carries a risk of inducing immediate hypersensitivity reactions.
- The case highlights a direct correlation between latex allergen exposure during diagnostic testing and severe anaphylactic episodes.
Implications:
- Skin tests must be conducted under strict medical supervision to enable immediate management of potentially life-threatening anaphylaxis.
- Healthcare facilities should implement robust protocols for allergen testing and anaphylaxis management to ensure patient safety.
- This case underscores the importance of recognizing and managing occupational allergies in healthcare professionals.
Related Concept Videos
Data Reporting and Recording
Types of Reports I: Hands-off Report
Following are the key components and categories of hand-off reports:
Purpose and Process:
Types of Reports II: Incident or Occurrence Report
Purposes:
In the healthcare industry, reports play a crucial role in documenting incidents within an agency. The primary objective of these reports is to ensure patient safety, uphold the...
Types of Reports III: Telephone and Verbal Reports
Here's an overview of each type:
Telephone Orders
Reporter Genes
Introduction to Documentation and Reporting
Nursing documentation records essential information and details regarding a patient's care and treatment in written or electronic form. It is a critical aspect of nursing practice that involves documenting assessments, interventions, outcomes, and other relevant details about a patient's health status.
Documentation maps the patient's health journey by creating a comprehensive...

