Related Experiment Video
Updated: Feb 9, 2026

Visualizing the Beating Heart in Drosophila
Published on: September 28, 2009
On-Pump Beating/Non-Beating CABG in Stable Angina Have Similar Outcomes
Victor Dayan1,2, Juan Jose Paganini1, Alvaro Marichal1
1Centro Cardiovascular Universitario, Hospital de Clinicas, Universidad de la Republica Oriental del Uruguay. Montevideo, Uruguay.
Insights
On-pump beating coronary artery bypass grafting (CABG) shows similar survival to conventional CABG in stable angina patients. Beating CABG is linked to higher glucose levels and ventilator use, while conventional CABG requires more inotropic support.
Area of Science:
- Cardiovascular Surgery
- Cardiac Anesthesia
- Thoracic Surgery
Background:
- Coronary artery bypass grafting (CABG) is a common procedure.
- On-pump beating CABG has been studied in patients with unstable angina or severe left ventricular dysfunction.
- Evidence is limited for on-pump beating CABG in stable angina with normal left ventricular function.
Purpose of the Study:
- To compare postoperative outcomes of on-pump beating versus non-beating CABG.
- To evaluate the safety and efficacy of both techniques in stable angina patients.
- To identify factors influencing outcomes in on-pump CABG.
Main Methods:
- A retrospective study of 1,145 patients undergoing on-pump isolated CABG.
- Patients were divided into beating and non-beating CABG groups.
- Outcomes included operative mortality, long-term survival, and need for inotropic/ventilator support.
Main Results:
- No significant differences in operative mortality, stroke, or long-term survival between beating and non-beating CABG groups.
- Patients undergoing non-beating CABG (with aortic cross-clamp) had higher intraoperative glycemia and prolonged mechanical ventilation.
- Patients undergoing beating CABG had a lower incidence of prolonged inotropic support.
Conclusions:
- On-pump beating CABG offers comparable operative mortality and long-term survival to conventional CABG with aortic cross-clamp.
- On-pump beating CABG is associated with higher intraoperative glycemia and increased need for mechanical ventilation.
- Conventional CABG with aortic cross-clamp is associated with a higher need for inotropic support.
- Both techniques are safe, allowing surgeon preference.
Objective:
On pump beating/non-beating coronary artery bypass grafts (CABG) has been compared in patients with unstable angina and/or severe left ventricular dysfunction. There is scarce evidence regarding the beneficial use of on-pump beating CABG in patients with stable angina and normal left ventricular function. Our aim was to study the postoperative results using both techniques in this group of patients.
Methods:
One thousand one hundred and forty-five patients with stable angina underwent on-pump isolated CABG in Uruguay from 2011 to 2015. Patients were grouped into beating/non-beating CABG. Operative mortality and long-term survival were evaluated as primary outcome. Logistic regression analysis was performed to define the predictive role of aortic cross clamp (AXC) on prolonged inotropic support, ventilator support and intraoperative glycemia.
Results:
Among the included patients, 988 underwent aortic cross clamp. No differences were found in operative mortality, stroke and long-term survival among both groups. Patients without AXC showed higher intraoperative values of glycemia and higher incidence of postoperative prolonged mechanical ventilator support (7.6% vs. 2.4%; P=0.001). The need for prolonged inotropic support was lower in this group of patients (27.4% vs. 49.5%; P<0.001).
Conclusion:
On-pump beating CABG has similar operative mortality and long-term survival compared with conventional AXC. Higher intraoperative glycemia and higher incidence for prolonged mechanical ventilator is associated with on-pump beating CABG. On the contrary, higher incidence for prolonged inotropic support is associated with AXC. Taking these factors into consideration, both techniques are safe and allow the surgeon to choose the most comfortable option.
More Related Videos
09:04Uncovering Beat Deafness: Detecting Rhythm Disorders with Synchronized Finger Tapping and Perceptual Timing Tasks
Published on: March 16, 2015
11:13Collection, Expansion, and Differentiation of Primary Human Nasal Epithelial Cell Models for Quantification of Cilia Beat Frequency
Published on: November 10, 2021
Related Concept Videos
Beats
Angina I: Introduction
Angina II: Classification
Angina IV: Management
Angina V: Nursing Management
ATP Driven Pumps III: V-type Pumps
The peripheral or cytosolic V1 domain with eight subunits is involved in ATP hydrolysis. The integral or transmembrane V0 domain containing at least five subunits...