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Updated: Feb 9, 2026

Culturing Microglia from the Neonatal and Adult Central Nervous System
Published on: August 9, 2013
Rituximab treatment in primary angiitis of the central nervous system
Shreeya Patel1, Laura Ross1,2, Shereen Oon1,2
1Department of Rheumatology, St Vincent's Hospital, Melbourne, Victoria, Australia.
Abstract:
Primary angiitis of the central nervous system (PACNS) is a rare autoimmune vasculitis affecting the brain and spinal cord. Treatment with biological agents has revolutionised the treatment of many rheumatic conditions but there is scant literature regarding the use of biological agents in PACNS. We present three cases of PACNS treated with rituximab, including two cases of relapsed disease, and a literature review suggesting a role for rituximab in this condition.
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