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Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis
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Palmoplantar Keratoderma with Keratoconus.

Ved Prakash Gupta1, Isha Chaudhari1

  • 1Department of Ophthalmology, University College of Medical Sciences and GTB Hospital, New Delhi, India.

Middle East African Journal of Ophthalmology
|June 15, 2018
PubMed
Summary
This summary is machine-generated.

Palmoplantar keratodermas (PPKs) involve skin thickening on palms and soles. This study details a rare case of bilateral keratoconus, an eye condition, occurring in a patient with PPK for the first time.

Keywords:
Keratoconuspalmoplantar keratodermaskeletal abnormalities

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Area of Science:

  • Ophthalmology and Dermatology
  • Genetics and Rare Diseases

Background:

  • Palmoplantar keratodermas (PPKs) are a group of rare genetic skin disorders.
  • PPKs manifest as abnormal skin thickening on the palms and soles.
  • Ocular findings like scleral melanosis and congenital cataracts are known associations.

Observation:

  • A patient with a known diagnosis of Palmoplantar Keratoderma presented for evaluation.
  • The patient exhibited symptoms and signs indicative of keratoconus affecting both eyes.
  • This represents a previously undocumented association between PPK and keratoconus.

Findings:

  • The study reports the first documented instance of bilateral keratoconus in an individual with PPK.
  • This finding expands the spectrum of known ocular manifestations associated with PPK.
  • Detailed clinical and diagnostic data of the patient are presented.

Implications:

  • Highlights the importance of comprehensive ophthalmological screening in patients diagnosed with PPK.
  • Suggests a potential underlying genetic or systemic link between PPK and keratoconus.
  • Contributes to a better understanding of the heterogeneity of PPK and its associated conditions.