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Assays for Validating Histone Acetyltransferase Inhibitors
Published on: August 6, 2020
Clinical validation of the Tempus xO assay
Nike Beaubier1, Robert Tell1, Robert Huether1
1Tempus Labs, Inc., Chicago, Illinois 60654, USA.
Abstract:
We have developed a clinically validated NGS assay that includes tumor, germline and RNA sequencing. We apply this assay to clinical specimens and cell lines, and we demonstrate a clinical sensitivity of 98.4% and positive predictive value of 100% for the clinically actionable variants measured by the assay. We also demonstrate highly accurate copy number measurements and gene rearrangement identification.
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