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Updated: Feb 9, 2026

Author Spotlight: Porphyrin-Modified Beads for Use as Compensation Controls in Flow Cytometry
Published on: March 24, 2023
Hydrogen gas generation using a metal-free fluorinated porphyrin
Yanyu Wu1, Nancy Rodríguez-López1, Dino Villagrán1
1Department of Chemistry and Biochemistry , The University of Texas at El Paso , El Paso , TX 79968 , USA .
Abstract:
Free-base meso-tetra(pentafluorophenyl)porphyrin, 1, is electrocatalytically active for hydrogen gas generation in the presence of p-toluenesulfonic acid. The electrochemical potential of hydrogen evolution (-1.31 V vs. Fc/Fc+ in THF) is comparable to those of metal containing electrocatalysts such as metallated porphyrins or other metallated macrocycles. Combining experimental observations and DFT computations, we propose the most favorable hydrogen generation mechanism to be a (1) reduction, (2) protonation, (3) reduction, (4) protonation (E-P-E-P) pathway.
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