Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Meristems and Plant Growth02:36

Meristems and Plant Growth

49.6K
Plants grow throughout their lives; this is called indeterminate growth, and it distinguishes plants from most animals. Although certain parts of plants stop growing (e.g., leaves and flowers), others grow continuously—like roots and stems.
49.6K
Population Growth00:57

Population Growth

28.7K
Population size is dynamic, increasing with birth rates and immigration, and decreasing with death rates and emigration. In ideal conditions with unlimited resources, populations can increase exponentially, which plots as a J-shaped growth rate curve of population size against time. This type of curve is characteristic of newly-introduced invasive species, or populations that have suffered catastrophic declines and are rebounding.
28.7K
Relationship Growth01:27

Relationship Growth

224
Interpersonal relationships progress through stages, beginning with awareness and moving toward mutuality, where emotional connections deepen. While many relationships remain at moderate levels of mutuality, deeper connections form through self-disclosure, trust, and interdependence.Self-DisclosureSelf-disclosure involves revealing personal information, starting with surface-level details and gradually progressing to more intimate content. As trust grows, individuals feel more comfortable...
224
Exponential Growth01:29

Exponential Growth

68
Bacterial populations exhibit exponential growth when conditions such as nutrient availability and temperature are favorable. In this phase, cells reproduce through binary fission, where each cell divides into two identical daughter cells. This process causes the population to double at regular intervals, resulting in a growth rate that is directly proportional to the current number of cells. As the population increases, the number of new cells formed during each generation also grows, creating...
68
Primary and Secondary Growth in Roots and Shoots03:02

Primary and Secondary Growth in Roots and Shoots

60.6K
Vascular plants, which account for over 90% of the Earth’s vegetation, all undergo primary growth—which lengthens roots and shoots. Many land plants, notably woody plants, also undergo secondary growth—which thickens roots and shoots.
60.6K
Growth versus Fixed Mindset01:24

Growth versus Fixed Mindset

310
Carol Dweck introduced the term mindset to describe individuals' beliefs about their intellectual and personal capabilities. These beliefs significantly influence psychological processes such as motivation, goal-setting, and perseverance, ultimately shaping academic and life outcomes. Individuals generally possess one of two mindsets- a fixed or a growth mindset—each promoting different responses to success, failure, and challenge.Fixed vs. Growth MindsetA fixed mindset assumes that one's...
310

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Nanocomplexes Integrated into a Polymeric Bilayer Film Enhance Buccal Permeation of a GLP-1 Peptide Analogue.

ACS applied materials & interfaces·2026
Same author

A Standardized Ex Vivo Porcine Oromucosal Model for Evaluating Peptide Fluxes.

Journal of visualized experiments : JoVE·2026
Same author

Tissue removal inside the beating heart using a robotically delivered metal MEMS tool.

The International journal of robotics research·2026
Same author

Systematic Engineering of Intra-Articular Drug Release Profiles Reveals a Key Determinant of Disease-Modifying Efficacy in Post-Traumatic Osteoarthritis.

bioRxiv : the preprint server for biology·2026
Same author

A glycan-based adjuvant expands the breadth and duration of protection of mRNA-based vaccines.

Nature immunology·2026
Same author

High-Resolution CT-Based Virtual Simulation of an Unruptured Sinus of Valsalva Aneurysm for Aortic Root Reimplantation: A Case Report.

Surgical case reports·2026

Related Experiment Video

Updated: Feb 9, 2026

Quantification of Oculomotor Responses and Accommodation Through Instrumentation and Analysis Toolboxes
08:27

Quantification of Oculomotor Responses and Accommodation Through Instrumentation and Analysis Toolboxes

Published on: March 3, 2023

1.5K

A Growth-Accommodating Implant for Paediatric Applications.

Eric N Feins1, Yuhan Lee2, Eoin D O'Cearbhaill2,3

  • 1Department of Cardiac Surgery, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA, 02115, USA.

Nature Biomedical Engineering
|June 15, 2018
PubMed
Summary

This study introduces a novel biodegradable medical implant designed for children. The implant expands to accommodate natural tissue growth, reducing the need for repeat surgeries and improving patient outcomes.

More Related Videos

Electrically Evoked Stapedius Reflex Measurements in Cochlear Implantation and Its Application in the Postoperative Fitting Process
07:00

Electrically Evoked Stapedius Reflex Measurements in Cochlear Implantation and Its Application in the Postoperative Fitting Process

Published on: June 21, 2024

1.5K
Simulating the Mechanics of Lens Accommodation via a Manual Lens Stretcher
05:14

Simulating the Mechanics of Lens Accommodation via a Manual Lens Stretcher

Published on: February 23, 2018

7.2K

Related Experiment Videos

Last Updated: Feb 9, 2026

Quantification of Oculomotor Responses and Accommodation Through Instrumentation and Analysis Toolboxes
08:27

Quantification of Oculomotor Responses and Accommodation Through Instrumentation and Analysis Toolboxes

Published on: March 3, 2023

1.5K
Electrically Evoked Stapedius Reflex Measurements in Cochlear Implantation and Its Application in the Postoperative Fitting Process
07:00

Electrically Evoked Stapedius Reflex Measurements in Cochlear Implantation and Its Application in the Postoperative Fitting Process

Published on: June 21, 2024

1.5K
Simulating the Mechanics of Lens Accommodation via a Manual Lens Stretcher
05:14

Simulating the Mechanics of Lens Accommodation via a Manual Lens Stretcher

Published on: February 23, 2018

7.2K

Area of Science:

  • Biomaterials Science
  • Pediatric Medical Devices
  • Regenerative Medicine

Background:

  • Current pediatric medical implants are often fixed-size, necessitating replacement or removal due to tissue growth.
  • This leads to repeated interventions, increased complications, and poorer outcomes in children.
  • There is a significant unmet need for implants that can adapt to and accommodate natural tissue growth.

Purpose of the Study:

  • To design and evaluate a novel growth-accommodating medical device for pediatric applications.
  • To demonstrate the device's ability to expand and accommodate tissue growth in vivo.
  • To validate the predictability and tunability of the device's behavior for patient-specific needs.

Main Methods:

  • Development of a device with a biodegradable core and a tubular braided sleeve.
  • Mathematical modeling to predict device behavior.
  • Ex vivo experiments using swine hearts and in vivo studies using rat tibia and piglet heart valve models.

Main Results:

  • The biodegradable core's degradation enables controlled sleeve and device elongation.
  • Mathematical modeling and ex vivo experiments confirmed predictable and tunable device behavior.
  • In vivo studies demonstrated successful tissue growth accommodation through polymer degradation and device expansion.

Conclusions:

  • The developed growth-accommodating device shows promise for pediatric applications.
  • Biodegradable core degradation allows for in vivo expansion, accommodating tissue growth.
  • This technology could reduce the need for revision surgeries in pediatric patients.