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Updated: Feb 9, 2026

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation
09:05

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation

Published on: October 20, 2016

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Dataset on the use of 3D speckle tracking echocardiography in light-chain amyloidosis

Antonio Vitarelli1, Maria Teresa Petrucci1, Silvia Lai1

  • 1Depts of Cardiology, Hematology and Medicine, Sapienza University, Rome, Italy.

Data in Brief
|June 15, 2018
PubMed

Insights

Three-dimensional speckle-tracking echocardiography (3DSTE) effectively differentiates cardiac amyloidosis (CA) from other hypertrophic cardiomyopathies. Combined analysis of left and right ventricular parameters shows high diagnostic accuracy for CA.

Area of Science:

  • Cardiology
  • Medical Imaging
  • Biomedical Engineering

Background:

  • Cardiac amyloidosis (CA) presents challenges in differentiation from other myocardial hypertrophic conditions.
  • Accurate diagnosis is crucial for appropriate patient management and treatment strategies.

Purpose of the Study:

  • To evaluate the utility of three-dimensional speckle-tracking echocardiography (3DSTE) in diagnosing CA.
  • To differentiate CA from other forms of myocardial hypertrophy using 3DSTE-derived parameters.

Main Methods:

  • Utilized 3DSTE to assess left ventricular (LV) and right ventricular (RV) deformation and rotational parameters.
  • Analyzed specific parameters including LV basal longitudinal strain, LV basal rotation, and RV basal longitudinal strain.

Main Results:

  • The combined assessment of LV basal longitudinal strain, LV basal rotation, and RV basal longitudinal strain demonstrated significant discriminative power for CA detection.
  • 3DSTE parameters provide valuable insights into biventricular function in CA.

Conclusions:

  • 3DSTE offers a promising non-invasive tool for diagnosing cardiac amyloidosis.
  • Biventricular assessment using 3DSTE aids in differentiating CA from other hypertrophic cardiomyopathies.

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