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Endoscopic optical coherence tomography with a flexible fiber bundle.

Lara M Wurster1, Laurin Ginner1,2, Abhishek Kumar1

  • 1Medical University of Vienna, Center for Medical Physics and Biomedical Engineering, Vienna, Austria.

Journal of Biomedical Optics
|June 15, 2018
PubMed
Summary

This study introduces a simplified endoscopic optical coherence tomography (OCT) design using a flexible fiber bundle (FB) for forward imaging. We identified optimal FB parameters to improve image quality in endoscopic OCT applications.

Keywords:
endoscopyfiber bundleoptical coherence tomography

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Area of Science:

  • Biomedical Optics
  • Medical Imaging
  • Endoscopy

Background:

  • Conventional endoscopic optical coherence tomography (OCT) systems often require complex distal probe designs with integrated beam steering components.
  • Forward-looking OCT imaging is crucial for various diagnostic and interventional procedures within the body.
  • Existing fiber bundle (FB) based OCT methods face challenges like multimoding and cross-coupling, affecting image quality.

Purpose of the Study:

  • To demonstrate in vivo endoscopic OCT imaging in the forward direction using a simplified flexible fiber bundle (FB) approach.
  • To analyze and overcome challenges associated with FB-based OCT, including multimoding and cross-coupling.
  • To identify optimal FB parameters for enhanced endoscopic OCT imaging performance.

Main Methods:

  • Developed a novel endoscopic OCT system utilizing a flexible fiber bundle (FB) for forward imaging.
  • Implemented a 2D scanning of a focused light beam on the proximal FB surface, eliminating distal beam steering.
  • Evaluated the performance of various FBs with differing numerical apertures, core sizes, core structures, and flexibility.

Main Results:

  • Successfully demonstrated in vivo endoscopic OCT imaging using the simplified FB design.
  • Characterized image quality degrading artifacts, such as multimoding and cross-coupling, in FB-based OCT.
  • Identified specific FB parameters that significantly influence image quality and system performance.

Conclusions:

  • The proposed FB-based endoscopic OCT approach simplifies endoscope design by removing distal beam steering.
  • Understanding and mitigating FB-specific artifacts are critical for high-quality endoscopic OCT imaging.
  • An optimal FB design, considering factors like numerical aperture and core structure, is proposed for improved endoscopic OCT applications.