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Cephalometric aspects of thalassemic children in the Indian subcontinent: A cross-sectional study

Amit Anand Samba1, Praveen Haricharan Bhoopathi2, Rajasekaran Meenakshi Sundaram3

  • 1Department of Pedodontics, Malla Reddy Institute for Dental Sciences, Hyderabad, Telangana, India.

Indian Journal of Dental Research : Official Publication of Indian Society for Dental Research
|June 15, 2018
PubMed

Insights

Thalassemic children in the Indian subcontinent exhibit distinct cephalometric differences, including a shorter anterior cranial base and a retrognathic mandible. These findings suggest a Class II profile in affected individuals compared to controls.

Area of Science:

  • Orthodontics
  • Pediatric Hematology
  • Craniofacial Development

Background:

  • Thalassemia is a genetic blood disorder prevalent in the Indian subcontinent.
  • Craniofacial abnormalities are potential complications of thalassemia.
  • Understanding these cephalometric variations is crucial for managing thalassemic patients.

Purpose of the Study:

  • To compare cephalometric characteristics of thalassemic children with a control group.
  • To identify specific craniofacial differences in thalassemic children from the Indian subcontinent.
  • To correlate cephalometric findings with the overall skeletal profile.

Main Methods:

  • Cephalometric analysis was performed on 31 thalassemic children and matched controls.
  • Measurements included anterior cranial base length, maxillary/mandibular angle, mandibular length, and SNB angle.
  • Wiley's analysis was used to assess relative maxillary prognathism.

Main Results:

  • Thalassemic children showed a shorter anterior cranial base length (Group I).
  • A smaller maxillary/mandibular angle and shorter mandibular length were observed (Group II).
  • The SNB angle was reduced, indicating maxillary prognathism in both male and female thalassemic subjects (Group III).

Conclusions:

  • Thalassemic children present with a retruded maxilla and a retrognathic mandible.
  • A Class II facial profile is characteristic of thalassemic individuals in this cohort.
  • Cephalometric analysis highlights significant craniofacial alterations in thalassemic children.
Abstract

Keywords:
Cephalometrycraniofacial growththalassemia

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