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Renal dysfunction significantly impairs the renal clearance of drugs, leading to potential complications in drug therapy. Renal failure, which can be caused by various factors, poses a significant challenge in the elimination of drugs from the body.
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Renal Subcapsular Transplantation of 2'-Deoxyguanosine-Treated Murine Embryonic Thymus in Nude Mice
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[Subcapsular renal hematomas after ureteroscopic lithotripsy].

B G Guliev1, B K Komyakov1, A Yu Zaikin1

  • 1Department of Urology, I.I. Mechnikov North-Western State Medical University, Saint-Petersburg, Russia.

Urologiia (Moscow, Russia : 1999)
|June 15, 2018
PubMed
Summary

Renal hematomas (RH) are a rare complication of retrograde endoscopic lithotripsy (REL), occurring in 0.3% of patients. Early detection of flank pain, fever, and anemia is crucial for timely diagnosis and patient-specific management.

Keywords:
complicationslithotripsyrenal hematomastonetreatmentureterureteroscopyurolithiasis

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Area of Science:

  • Urology
  • Endourology
  • Nephrology

Background:

  • Renal hematomas (RH) are an uncommon complication following retrograde endoscopic lithotripsy (REL).
  • Understanding the incidence and etiological factors of RH after REL is essential for patient care.

Purpose of the Study:

  • To investigate the incidence and causes of renal hematomas (RH) after retrograde endoscopic lithotripsy (REL).
  • To analyze patient demographics, stone characteristics, and pre-existing conditions associated with RH development.

Main Methods:

  • A retrospective analysis of 1214 retrograde endoscopic lithotripsy (REL) procedures performed between 2001 and 2016.
  • Evaluation of patient data including age, gender, surgical history, comorbidities, kidney function, stone burden, hydronephrosis, and diagnostic imaging (ultrasound, SCT).

Main Results:

  • Four cases (0.3%) of renal hematomas (RH) were identified in patients with obstructive upper ureteral stones (0.8-1.2 cm).
  • Associated symptoms included flank pain, fever, and anemia. Three patients had a history of upper urinary tract (UUT) surgery.
  • Management varied from conservative therapy to surgical intervention, with complete resolution observed on follow-up imaging.

Conclusions:

  • Renal hematomas (RH) are a rare but significant complication of retrograde endoscopic lithotripsy (REL).
  • Clinical presentation of flank pain, fever, and anemia warrants kidney ultrasound for RH diagnosis.
  • Treatment strategies for RH should be individualized based on clinical severity and patient condition.