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[Rapid screening of three halogenated salicylanilines in cosmetics using ambient ionization coupled with ion mobility
Xiangyu Guo1, Qiang Ma1, Xianshuang Meng1
1Chinese Academy of Inspection and Quarantine, Beijing 100176, China.
Objective:
A rapid analytical method had been developed for the screening of three halogenated salicylanilines in cosmetics using ambition ionization coupled with ion mobility spectrometry.
Methods:
Without time-consuming pretreatment, cosmetic samples of lotion, lipstick and powder were added or smudged onto a Grade 3MM chromatography paper for paper spray ionization, cosmetic samples of cream and shampoo were simply loaded with a metal wire probe for extraction nano-electrospray.
Results:
The limits of detection( LODs) for the three halogenated salicylanilides were 50 μg/kg. The instrumental analysis time for a single ion mobility spectrometry run was less than 15 ms. The suspected positive samples were subjected to further verification by high-performance liquid chromatography coupled with tandem mass spectrometry.
Conclusion:
The method is simple, rapid, and with low cost and is suitable for rapid, on-site screening of cosmetics.
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