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The Deese-Roediger-McDermott DRM Task: A Simple Cognitive Paradigm to Investigate False Memories in the Laboratory
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Laboratory investigations.

Eugen Boltshauser1, Konrad P Weber1

  • 1Department of Pediatric Neurology, University Children's Hospital, University of Zurich, Zurich, Switzerland; Departments of Neurology and Ophthalmology, University Hospital Zurich, University of Zurich, Switzerland.

Handbook of Clinical Neurology
|June 16, 2018
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Summary
This summary is machine-generated.

This chapter outlines chemical and hematologic tests for diagnosing cerebellar ataxias. Early detection of treatable metabolic causes like vitamin E deficiency is emphasized.

Keywords:
acquired ataxiaautoimmune ataxiadiagnostic workuphereditary ataxialaboratory investigationstreatable ataxia

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Area of Science:

  • Neurology
  • Clinical Chemistry
  • Hematology

Background:

  • Subacute to chronic cerebellar ataxias require comprehensive diagnostic workup.
  • Identifying treatable causes is crucial for effective patient management.

Purpose of the Study:

  • To review chemical and hematologic investigations for diagnosing cerebellar ataxias.
  • To highlight early diagnosis of treatable metabolic and autoimmune ataxias.

Main Methods:

  • Discussion of relevant blood (serum, plasma), urine, and cerebrospinal fluid investigations.
  • Consideration of specific metabolic disorders (e.g., abetalipoproteinemia, vitamin E deficiency) and autoimmune conditions.

Main Results:

  • Key diagnostic tests for various cerebellar ataxias are presented.
  • Emphasis on age-specific reference values for accurate interpretation.

Conclusions:

  • Diagnostic test selection should be guided by clinical context, including patient history, age, and neurological findings.
  • Integrated approach considering hematologic, chemical, and cerebrospinal fluid analysis aids in diagnosing cerebellar ataxias.