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Related Experiment Video

Updated: Feb 9, 2026

In ovo Expression of MicroRNA in Ventral Chick Midbrain
09:19

In ovo Expression of MicroRNA in Ventral Chick Midbrain

Published on: September 16, 2013

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Embryology.

Parthiv Haldipur1, Derek Dang1, Kathleen J Millen2

  • 1Seattle Children's Research Institute, Center for Integrative Brain Research, Seattle, WA, United States.

Handbook of Clinical Neurology
|June 16, 2018
PubMed
Summary
This summary is machine-generated.

Understanding cerebellar development is crucial for addressing human cerebellar disorders. Research in mouse models provides key insights into the molecular regulators and cellular processes involved in forming the mature cerebellum.

Keywords:
cerebellumdevelopmentfoliationhistogenesishumanmalformationmouseneuronal specificationsignaling

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Area of Science:

  • Neuroscience
  • Developmental Biology
  • Genetics

Background:

  • Human cerebellar disorders are increasingly recognized.
  • Understanding cerebellar development is essential for studying these disorders.

Purpose of the Study:

  • To provide an overview of cerebellar development.
  • To highlight key molecular regulators and cellular processes.

Main Methods:

  • Analysis of animal models, primarily mice.
  • Focus on genetic manipulation in mice.

Main Results:

  • Detailed description of cerebellar development epochs.
  • Identification of key molecular regulators.
  • Explanation of cell genesis, migration, and rearrangement.

Conclusions:

  • Mouse cerebellar development offers insights into human disorders.
  • Human fetal development research is crucial for understanding human-specific features.