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Neurophysiology of gait
Mariano Serrao1, Alberto Ranavolo2, Carlo Casali1
1Department of Medical and Surgical Sciences and Biotechnologies, University of Rome Sapienza, Latina, Italy.
Handbook of Clinical Neurology
|June 16, 2018
Summary
Cerebellar ataxia impairs gait and balance, causing wider steps and increased variability. Motion analysis quantifies these deficits, aiding targeted rehabilitation strategies for improved patient mobility.
Area of Science:
- Neuroscience
- Biomechanics
- Rehabilitation Medicine
Background:
- Cerebellar ataxias present with significant gait and balance dysfunction.
- Traditional clinical descriptions are enhanced by quantitative motion analysis.
Purpose of the Study:
- To quantitatively characterize gait and balance abnormalities in cerebellar ataxia using motion analysis.
- To establish a basis for developing and assessing rehabilitation strategies.
Main Methods:
- Utilized modern motion analysis systems to collect kinematic, kinetic, and surface electromyography data.
- Compared gait parameters of cerebellar ataxia patients with healthy subjects.
Main Results:
- Cerebellar ataxia patients exhibit increased step width, reduced ankle range of motion, and greater stride-to-stride variability.
- Progressive disease leads to reduced step length and lower-limb joint motion.
- Poor intersegmental coordination, particularly between trunk and hip, causes upper-body oscillations.
Conclusions:
- Motion analysis provides a detailed characterization of gait impairment in cerebellar ataxia.
- Understanding these deficits is crucial for developing effective, targeted rehabilitation interventions.

