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In operant conditioning, the timing of reinforcement is crucial. For animals like rats and cats, immediate reinforcement (within a few seconds) is much more effective than delayed reinforcement. For example, a food reward for a rat needs to follow within 30 seconds of pressing a bar to be effective. 
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  • 1Quarraisha Abdool Karim (top) and Salim S. Abdool Karim (bottom) are professors at the Mailman School of Public Health at Columbia University, New York, NY, USA, and are the associate scientific director and director, respectively, of the Centre for the AIDS Programme of Research in South Africa (CAPRISA) at the University of KwaZulu-Natal, Durban, South Africa. quarraisha.abdoolkarim@caprisa.org salim.abdoolkarim@caprisa.org.

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