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Related Experiment Videos

Physicians' perspectives on receiving unsolicited genomic results.

Douglas B Pet1, Ingrid A Holm2,3, Janet L Williams4

  • 1Vanderbilt University School of Medicine, Nashville, Tennessee, USA.

Genetics in Medicine : Official Journal of the American College of Medical Genetics
|June 16, 2018
PubMed
Summary

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Physicians need clear pathways and clinical decision support for unsolicited genomic results (UGRs). Managing these results impacts patient care and healthcare workflows, requiring strategic integration.

Area of Science:

  • Genomic Medicine
  • Clinical Genetics
  • Health Informatics

Background:

  • Physicians are increasingly encountering unsolicited genomic results (UGRs) not directly ordered by them.
  • Understanding physician perspectives on UGRs is crucial for effective integration into clinical practice.

Purpose of the Study:

  • To explore physicians' perceptions of how unsolicited genomic results (UGRs) will affect them and their patients.
  • To identify physician concerns and needs regarding the management of UGRs.

Main Methods:

  • Conducted semistructured interviews with 25 adult and pediatric primary care and subspecialty physicians.
  • Interview topics included actionability, patient impact, workflow, results return, and responsibility for UGRs.

Main Results:

Keywords:
AttitudesEthicsPhysiciansReturn of research resultsUnsolicited genomic results

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  • Physicians prioritize actionable UGRs with clear evidence-based pathways and clinical decision support (CDS).
  • Concerns include potential patient harms (anxiety, false reassurance) and workflow challenges (unreimbursed time, response burden).
  • Disagreement exists among physicians regarding responsibility for managing UGRs.

Conclusions:

  • The influx of UGRs for healthy patients presents significant concerns for physicians.
  • Strategic integration of UGRs into healthcare workflows is essential for physicians to effectively manage these results and serve patients.
  • Physician responses inform the development of surveys and strategies for UGR management.