[The Microbiome - The Unscheduled Parameter for Future Therapies].

Area of Science:

• Otorhinolaryngology
• Microbiome research
• Human health

Background:

• The microbiome comprises diverse microorganisms (bacteria, viruses, parasites) residing on the body's surface.
• Significant variations in the microbiome exist within anatomical regions of otorhinolaryngology (ENT).

Purpose of the Study:

• To review current findings on the microbiome in the ear, nose, throat, larynx, and skin.
• To explore the relationship between microbiome composition and factors like age, diet, and lifestyle.
• To summarize emerging evidence on the microbiome's role in ENT diseases.

Main Methods:

• Literature review of recent scientific findings.
• Analysis of studies investigating microbiome interactions in the ENT area.
• Synthesis of data on common influencing factors (age, diet, lifestyle).

Main Results:

• Demonstrated significant divergence and variance in the microbiome across different ENT anatomical sites.
• Identified interactions between microbiome composition and factors such as age, diet, and smoking.
• Highlighted emerging insights into the microbiome's potential pathognomic role in ENT conditions.

Conclusions:

• The microbiome composition varies considerably within the otorhinolaryngology anatomical regions.
• Factors like age, diet, and lifestyle significantly influence these microbial communities.
• The microbiome shows potential as a key factor in the development and understanding of ENT diseases.