Related Experiment Video
Updated: Feb 8, 2026

Author Spotlight: Advancing Labor Management Through Electromyometrial Imaging for Understanding Uterine Contractions
Published on: May 26, 2023
Normal Serum Cystatin C Level during the First Trimester of Thai Pregnant Women
Background:
Cystatin C is a biomarker of renal function and other diseases. Physiologic changes during pregnancy can alter it level and lead to misinterpretation of result.
Objective:
To determine reference values for serum cystatin C in the first trimester of pregnancy.
Material And Method:
The Thai singleton uncomplicated pregnant women who attend antenatal clinic at Maha Chakri Sirindhorn Medical Center during August 2013 to December 2014 were included. Gestational age of individual was calculated by last menstrual period or ultrasound scan. Demographic data and obstetrics outcomes were recorded. Peripheral blood was taken on the first prenatal visit. Serum cystatin C was measured by particle-enhanced turbidimetric immunoassay (PETIA) with ARCHITECT c Systems® (ABBOTT, Germany).
Results:
A total of 48 pregnant women were eligible for the study. The overall mean and standard deviation of serum cystatin C was 0.58+0.08 mg/L. There was no significant correlation between serum cystatin C and creatinine level (r = 0.22, p-value = 0.13).
Conclusion:
The reference value of serum cystatin C was established for Thai pregnant women in the first trimester. Further studies of its correlation to specific obstetrics conditions should be considered.
Related Concept Videos
Normal Distribution
Normal Stress
When a rod is under axial loading, the internal forces and corresponding stress are normal to the plane of the section, so it is termed normal stress. It's important to...
Leveling Effect
Applications of Normal Distribution
The heights of 15 to 18-year-old males from Chile from 1984 to 1985 followed a normal distribution. The mean height is 172.36...
Introduction to Normal Distributions
High-Level and Low-Level Awareness

