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Related Experiment Video

Updated: Feb 8, 2026

Knotless Independent Double-Row Repair and Biceps Augmentation for Anterosuperior Rotator Cuff Tears
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Knotless Independent Double-Row Repair and Biceps Augmentation for Anterosuperior Rotator Cuff Tears

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Rotator Cuff Matrix Augmentation and Interposition: A Systematic Review and Meta-analysis.

James R Bailey1, Christopher Kim1, Eduard Alentorn-Geli2

  • 1Division of Sports Medicine and Shoulder Surgery, Department of Orthopaedic Surgery, Duke University Medical Center, Durham, North Carolina, USA.

The American Journal of Sports Medicine
|June 16, 2018
PubMed
Summary
This summary is machine-generated.

Graft augmentation for rotator cuff repair (RCR) may reduce retear rates and improve shoulder function compared to RCR alone. Further research is needed to confirm these findings for rotator cuff tears.

Keywords:
allograftaugmentationautograftgraftpatchrepairrotator cuff tearshoulderxenograft

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Area of Science:

  • Orthopedic Surgery
  • Biomaterials Science

Background:

  • Rotator cuff tears present complex surgical management challenges.
  • Treatment options range from conservative approaches to advanced reconstructive procedures.

Purpose of the Study:

  • To systematically review and evaluate outcomes of graft augmentation/interposition versus rotator cuff repair (RCR) alone.
  • To conduct a meta-analysis comparing graft use to RCR alone for superior outcomes.

Main Methods:

  • Systematic review and meta-analysis of electronic literature searches (Medline, Embase, CINAHL).
  • Inclusion criteria: minimum 1-year follow-up, 10+ participants, clinical results of RCR with augmentation/interposition or RCR alone.
  • Risk of bias assessment and meta-analysis of comparative studies.

Main Results:

  • 36 studies included in the review; 5 underwent meta-analysis.
  • Graft augmentation/interposition showed significantly lower retear rates (P=.05) and higher American Shoulder and Elbow Surgeons (ASES) scores (P=.005) versus RCR alone.
  • Improvements in UCLA scores and pain were not statistically significant.

Conclusions:

  • Graft augmentation or interposition may offer benefits in reducing retear rates and improving ASES scores compared to RCR alone.
  • No specific graft option demonstrated superiority due to study variability.
  • Further high-quality, prospective, randomized trials are necessary for definitive conclusions on graft use in RCR.