Surgical linear ablation for ventricular tachycardia with postinfarction ventricular aneurysm
Changcheng Liu1, Liangshan Wang1, Bo Li1
1Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China; Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing, China.
The Journal of Surgical Research
|June 17, 2018
Summary
Surgical radial linear ablation is a feasible approach for treating ventricular tachycardia (VT) in left ventricular aneurysm (LVA) models. This method demonstrated significant acute freedom from VT, offering a promising alternative to traditional treatments.
Area of Science:
- Cardiology
- Cardiac Surgery
- Electrophysiology
Background:
- Left ventricular aneurysm (LVA) is associated with ventricular tachycardia (VT).
- Current treatments like endocardiectomy and cryoablation for VT in LVA can cause significant myocardial damage.
- Electrophysiological mapping-guided surgical ablation offers a potential alternative.
Purpose of the Study:
- To evaluate the feasibility of surgical radial linear ablation for VT in a left ventricular aneurysm (LVA) porcine model.
- To assess the efficacy of this technique guided by electrophysiological mapping.
Main Methods:
- A porcine model of VT with LVA was developed.
- Endocardial and epicardial substrate mapping was performed under thoracotomy.
- Surgical radial linear ablation was executed using a bipolar radiofrequency device.
Main Results:
- Left ventricular aneurysm (LVA) developed in 86.67% of pigs, with 28 sustained monomorphic ventricular tachycardias (VTs) initiated.
- Abnormal electrophysiological potentials were identified on the border zone of LVA.
- Eight continuous linear lesions were created per animal, achieving 84.62% acute freedom from VT (P < 0.05).
Conclusions:
- Surgical linear endo-epicardial ablation is a feasible strategy for managing VT in LVA.
- This approach shows promise in reducing VT burden in LVA models.
Keywords:
Left ventricular aneurysmLinear ablationSubstrate mappingSurgical ablationVentricular tachycardiaMore Related Videos
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