Antibiotics Protect against Liver Tumors in Mice

    Cancer Discovery
    |June 17, 2018
    PubMed

    Insights

    Depleting gut bacteria in mice boosted liver bile acids, increasing natural killer T cells to protect against tumors. This gut microbiome mechanism may offer new cancer prevention strategies.

    Area of Science:

    • Immunology
    • Microbiology
    • Hepatology

    Background:

    • The gut microbiome plays a crucial role in host health and disease.
    • Liver cancer development is influenced by various factors, including inflammation and immune surveillance.

    Related Concept Videos

    Antibiotic Selection00:57

    Antibiotic Selection

    Overview
    60.0K
    Protection of Alcohols02:31

    Protection of Alcohols

    This lesson delves into the concept of protection and deprotection of a functional group fundamental to synthetic organic chemistry. These phenomena are explained in the context of aliphatic and aromatic alcohols.
    Protection
    It defines a protecting group as the masking agent to make the more reactive species inert to a given set of conditions. This concept is depicted via the illustration of liquid flow through different outlets in an assembly of pipes. The analogy helps to understand the role...
    8.1K
    Zones of Protection01:16

    Zones of Protection

    In power systems, the entire setup is divided into protective zones to isolate faults and protect the rest of the network. These zones include generators, transformers, buses, transmission lines, distribution lines, and motors. Each zone can be visualized as a separate room in a house, with each room protected by its own circuit breaker.
    Protective zones are defined by closed dashed lines, containing one or more components. A key characteristic of these zones is the strategic placement of...
    808
    Radial System Protection01:23

    Radial System Protection

    Radial systems employ time-delay overcurrent relays to reduce load interruptions. When a fault occurs, the nearest breaker opens first, while upstream breakers remain closed due to longer delay settings. This approach ensures minimal disruption to the rest of the system.
    In a radial system with a fault downstream of the third breaker, ideally, only the third breaker will open, isolating the fault and interrupting the load connected beyond it. The second breaker has a longer delay setting,...
    447
    Protecting Self-Esteem01:27

    Protecting Self-Esteem

    Self-esteem, a central component of psychological well-being, is actively maintained through various cognitive and behavioral strategies. Individuals employ specific mechanisms to preserve a positive self-concept and mitigate threats to their self-worth, particularly in contexts involving social evaluation or personal feedback. Four primary techniques are commonly used to sustain self-esteem.Manipulating AppraisalsOne prominent strategy involves manipulating appraisals from others. Individuals...
    227
    Development of Antibiotic Resistance01:30

    Development of Antibiotic Resistance

    Antibiotic resistance is a major public health concern that arises when bacteria evolve mechanisms to withstand the effects of antibiotic treatments. This resistance can be intrinsic, acquired through genetic mutations, or transferred between bacteria via horizontal gene transfer. The development of antibiotic resistance poses significant challenges in treating bacterial infections and necessitates ongoing research to develop new therapeutic strategies.Intrinsic resistance occurs when bacterial...
    1.5K