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A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
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A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting

Published on: January 12, 2018

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Neurologic Consequences of Preterm Birth

Margie A Ream1, Lenora Lehwald2

  • 1Division of Child Neurology, Nationwide Children's Hospital, 700 Children's Dr., Columbus, OH, 43205, USA. Margie.ream@nationwidechildrens.org.

Current Neurology and Neuroscience Reports
|June 17, 2018
PubMed

Insights

Premature birth impacts brain development, increasing risks for neurodevelopmental disabilities. Advances in understanding and technology offer new targets for interventions to improve outcomes for these children.

Area of Science:

  • Neonatal neuroscience
  • Developmental pediatrics
  • Neuroimaging

Background:

  • Preterm birth is a leading global cause of mortality in young children.
  • Increased survival rates for extremely preterm infants are associated with a higher incidence of long-term neurological impairments.
  • Understanding the impact of prematurity on brain development is crucial for improving long-term outcomes.

Purpose of the Study:

  • To review recent findings on brain development changes in preterm infants.
  • To examine the impact of prematurity on neurodevelopmental disabilities.
  • To identify potential targets for neuroprotection and improved outcomes.

Main Methods:

  • Review of advanced neuroimaging techniques.
  • Longitudinal follow-up studies of individuals born extremely preterm.
  • Analysis of risk factors for neurological impairment.

Main Results:

  • Preterm birth affects all aspects of neurological development.
  • Sensory impairments are linked to later cognitive and social deficits.
  • Advanced imaging and longitudinal studies reveal critical insights into neurodevelopmental trajectories.

Conclusions:

  • Early identification and intervention for sensory impairments are vital.
  • Further research is needed to develop prenatal and postnatal neuroprotective strategies.
  • Improving outcomes for preterm infants requires a comprehensive approach to neurodevelopmental care.
Abstract

Keywords:
Brain developmentCerebral palsyNeurodevelopmental disabilitiesPrematuritySensory impairmentSocial development

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