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Positive reinforcement targeting abstinence in substance misuse (PRAISe): Study protocol for a Cluster RCT & process
N Metrebian1, T Weaver2, S Pilling3
1King's College London, National Addiction Centre, Institute of Psychiatry, Psychology & Neuroscience, London, UK.
Contemporary Clinical Trials
|June 17, 2018
Summary
Contingency management (CM) offers incentives to boost attendance and reduce opiate use in treatment. This trial assessed CM
Area of Science:
- Addiction Medicine
- Clinical Psychology
- Health Services Research
Background:
- Opiate substitution treatment (OST) in England has high attrition and persistent illicit drug use.
- Contingency management (CM), using incentives, is recommended by NICE to improve OST outcomes.
- Evidence for CM delivery within UK National Health Service (NHS) addiction services is limited.
Purpose of the Study:
- To evaluate the feasibility, acceptability, clinical, and cost-effectiveness of CM in UK addiction services.
- To assess CM as an adjunct to OST for improving treatment attendance and reducing opiate use.
- To inform UK drug treatment policy and practice regarding CM implementation.
Main Methods:
- A cluster randomised controlled effectiveness trial (PRAISe trial) comparing CM (praise and financial incentives) with treatment as usual (TAU).
- CM targeted either opiate abstinence or treatment session attendance.
- Includes an economic evaluation and an embedded process evaluation.
Main Results:
- The study evaluated the feasibility, acceptability, clinical, and cost-effectiveness of CM interventions.
- Results will inform the implementation of CM alongside OST in UK addiction services.
- Identified contextual factors and mechanisms influencing CM effectiveness.
Conclusions:
- CM shows promise as an adjunct to OST for improving outcomes in opiate addiction treatment.
- The findings will guide UK drug treatment policy and practice for enhanced patient care.
- Further research may refine CM strategies for diverse patient populations.
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