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[Postural tachycardia syndrome (PoTS): An up-to-date]
L Astudillo1, A Laure2, V Fabry3
1Service de médecine interne, CHU Purpan, Toulouse, France; Institut national de la santé et de la recherche médicale (Inserm), UMR1037, France; Société de médecine, chirurgie et pharmacie de Toulouse, France.
La Revue De Medecine Interne
|June 18, 2018
Summary
Postural tachycardia syndrome (PoTS) is a condition causing rapid heart rate increase upon standing. It leads to fatigue and impacts quality of life, often requiring nonpharmacological and pharmacological treatments.
Area of Science:
- Cardiology
- Neurology
Background:
- Postural tachycardia syndrome (PoTS) is a complex condition characterized by an excessive heart rate increase upon standing.
- Symptoms include cerebral hypoperfusion, fatigue, and significantly reduced quality of life.
Purpose of the Study:
- To define Postural tachycardia syndrome (PoTS).
- To outline its associated conditions and treatment options.
Main Methods:
- Diagnosis involves monitoring heart rate changes within 10 minutes of standing or during a head-up tilt test.
- Absence of orthostatic hypotension is a key diagnostic criterion.
Main Results:
- PoTS is defined by a heart rate increase of ≥30 bpm upon standing without orthostatic hypotension.
- Symptoms are exacerbated in an upright position and relieved when supine.
Conclusions:
- PoTS is linked to various pathophysiological mechanisms and can co-occur with Ehlers-Danlos disease and autoimmune disorders.
- Treatment strategies include nonpharmacological interventions and medications like propranolol, fludrocortisone, or midodrine.
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