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[Postural tachycardia syndrome (PoTS): An up-to-date]
L Astudillo1, A Laure2, V Fabry3
1Service de médecine interne, CHU Purpan, Toulouse, France; Institut national de la santé et de la recherche médicale (Inserm), UMR1037, France; Société de médecine, chirurgie et pharmacie de Toulouse, France.
Abstract:
Postural tachycardia syndrome (PoTS) is a multifactorial syndrome defined by an increase in heart rate ≥30bpm, within 10minutes of standing (or during a head up tilt test to at least 60°), in absence of orthostatic hypotension. It is associated with symptoms of cerebral hypoperfusion that are worse when upright and improve in supine position. Patients have an intense fatigue with a high incidence on quality of life. This syndrome can be explained by many pathophysiological mechanisms. It can be associated with Ehlers-Danlos disease and some autoimmune disorders. The treatment is based on nonpharmacological measures and treatment with propranolol, fludrocortisone or midodrine.
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