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Graves' disease presenting as severe postpartum pruritus.
Rachel Marinch Carpenter1,2, Jessica Wongward2
1Family Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
BMJ Case Reports
|June 18, 2018
Summary
Postpartum pruritus associated with cholestasis may indicate undiagnosed Graves' disease. Treatment with methimazole resolved symptoms and normalized liver function by restoring euthyroid state.
Area of Science:
- Endocrinology
- Hepatology
- Obstetrics and Gynecology
Background:
- Pruritus is a common postpartum symptom, but persistent or worsening cases warrant thorough investigation.
- Cholestasis, a condition of impaired bile flow, can manifest with generalized pruritus.
- Undiagnosed endocrine disorders, such as autoimmune thyroid disease, can present with diverse symptoms postpartum.