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Updated: Feb 8, 2026

Frailty Assessment in an Aging Mouse Model
Published on: September 23, 2025
Knowledge and perceptions about aging and frailty: An integrative review of the literature
Abby Parish1, Jennifer Kim1, Kanah May Lewallen1
1Vanderbilt University School of Nursing, 461 21st Ave. South, Nashville, TN 36240.
Abstract:
A growing body of evidence indicates that biological aging or frailty is a determinant of health-related outcomes, however, frailty is likely poorly understood and under-recognized by the public-at-large. Using Whittemore and Knafl's methodology, we aimed to conduct an integrative review of research on public knowledge and perceptions of aging and frailty, and to create a conceptual model of our findings. Twenty-three studies are presented. The conceptual model suggests that culture, knowledge of aging, and stereotypes influence adults' beliefs and perceptions. Adults determine priorities about aging, and then subconsciously or consciously determine which parts of are controllable. If deemed controllable and important, they may participate in health behaviors to mediate aging. If deemed uncontrollable or less important, adults may aim to control their own peace of mind through acceptance. Scant findings suggest that frailty is a more subjective term in which participants often optimistically do not identify themselves as frail.
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