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A route to the total synthesis of iso-LTB4 system

D Pirillo, A Gazzaniga, P Leggeri

Il Farmaco; Edizione Scientifica

|April 1, 1985

Abstract:

The convergent synthesis of the iso-Leukotriene B4 (XVI) (as diastereoisomeric mixture with the desired geometry), by Wittig's condensation of the two precursor synthons at 6 (VI) and 14 C (XIV), starting from the common cyclic acrylaldehyde dimer (I), is reported.

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